Lymphoma

There are two major types of lymphoma:

  • Hodgkin's Lymphoma and
  • Non-Hodgkin's Lymphoma.

 

Non-Hodgkin's Lymphoma (NHL):

There are more than 30 subtypes of Non-Hodgkin’s lymphoma.
The most common types are low grade lymphoma (follicular lymphoma the most common) and diffuse large B-cell lymphoma.

 

Low grade lymphoma

  • is not curable and grows slowly and may or may not require treatment in the beginning.
  • Some patients remain well without lymphoma progressing for years.

 

Diffuse large B-cell lymphoma

 

Radiation therapy:

Some patients may require radiation therapy following completion of chemotherapy.

 

Hodgkin’s Lymphoma:

  • Hodgkin’s lymphoma is treated with a different type of chemotherapy.
  • The most commonly used chemotherapy regimen is called ABVD (Adriamycin, Bleomycin, Vincristine, Dacarbazine).

 

Radiation therapy:

Some patients may require radiation therapy following completion of chemotherapy.

 

Diagnosis:

Usually a biopsy (taking a small piece) of the growth is needed to establish a diagnosis.
Other tests, such as CT scan, PET scan, and MRI may also be ordered

Referral:

  • You may be referred to medical oncology after a biopsy has confirmed the diagnosis of lymphoma.
  • Your oncologist will discuss with you what type of lymphoma you have and what treatment options you may benefit from.

 

Common questions:

Can low grade lymphoma be cured? There is no cure at this time.

Can diffuse large B-cell lymphoma be cured? Yes.

Can Burkitt's lymphoma be cured? Yes.

Can mantle cell lymphoma be cured? There is no cure at this time.

 

Stem Cell Transplant:

Some patients who relapsed may be considered for stem cell transplant:

  • autologous or allogeneic.
  • Autologous means using a patient's own stem cells;
  • Allogeneic means using another person's stem cells (donor’s stem cells), from related or unrelated donor.
  • A patient who requires stem cell transplant will be referred to Stanford Medical Center Department of Bone Marrow Transplant.

When is stem cell transplant considered?

  • Patients with relapsed or refractory diffuse large B-cell lymphoma who respond to salvage chemotherapy.
  • Patients with mantle cell lymphoma are sometimes considered for allogeneic stem cell transplant.

Clinical trials available for treatment of lymphoma at Kaiser Permanente Santa Clara:

TOP

Santa Clara

Comprehensive Cancer Care